Spontaneous and induced leukemias of myeloid origin in recombinant inbred BXH mice
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منابع مشابه
Antibodies to Spontaneous and Methylcholaiithrene-induced Tumors in Inbred Mice
Isoimmunity to a methylcholanthrene-indueed fibrosarcoma and to a spontaneous breast adenocarcinoma was induced in female O3H/HeX mice. Circulating antitumor antibodies spé cifie for the particular immunizing tumor were detected in the immune mice. These antibodies did not appear until the primary tumors were surgically removed. Measurable amounts of anti body could be detected as long as 3.5 ...
متن کاملAntibodies to spontaneous and methylcholanthrene-induced tumors in inbred mice.
Isoimmunity to a methylcholanthrene-indueed fibrosarcoma and to a spontaneous breast adenocarcinoma was induced in female O3H/HeX mice. Circulating antitumor antibodies spé cifie for the particular immunizing tumor were detected in the immune mice. These antibodies did not appear until the primary tumors were surgically removed. Measurable amounts of anti body could be detected as long as 3.5 ...
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The seven CXB recombinant inbred strains were tested for susceptibility to Friend helper virus (F-MuLV) hematopoietic neoplasms. BALB/c and CXB-H mice develop erythroblastosis after neonatal inoculation with F-MuLV, while C57BL/6 and the six other RI strains develop lymphoma and myelogenous leukemia. This strain distribution pattern is different from that for H-2, Gpd-1 (linked to Fv-1), Fv-2, ...
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Recombinant inbred (RI) mice are frequently used to identify QTL that underlie differences in measurable phenotypes between two inbred strains of mice. Here we show that one RI strain, C57BL/6J x DBA/2J (BXD29), does not develop an inflammatory response following inhalation of LPS. Approximately 25% of F2 mice [F1(BXD29 x DBA/2J) x F1] are also unresponsive to inhaled LPS, suggesting the presen...
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The tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL/Apo-2L) is a member of the TNF superfamily that trigger and activate 2 death receptors, DR4 and DR5, and 2 decoy receptors, DcR1 and DcR2. Several studies demonstrated that TRAIL in monotherapy can induces cancer cell death cells, but few have been done in leukemias in combination with conventional drugs. The aim of this w...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1984
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.51.3.586-594.1984