Spontaneous Nε-methylation and Nε-formylation reactions between l-lysine and formaldehyde inhibited by l-ascorbic acid
نویسندگان
چکیده
منابع مشابه
Validation study to compare effects of processing protocols on measured Nε-(carboxymethyl)lysine and Nε-(carboxyethyl)lysine in blood
Epidemiological studies show that elevated plasma levels of advanced glycation end products (AGEs) are associated with diabetes, kidney disease, and heart disease. Thus AGEs have been used as disease progression markers. However, the effects of variations in biological sample processing procedures on the level of AGEs in plasma/serum samples have not been investigated. The objective of this inv...
متن کاملNε,Nε-Dimethyl-lysine cytochrome c as an NMR probe for lysine involvement in protein–protein complex formation
The reductively dimethylated derivatives of horse and yeast iso1-ferricytochromes c have been prepared and characterized for use as NMR probes of the complexes formed by cytochrome c with bovine liver cytochrome b & and yeast cytochrome c peroxidase. The electrostatic properties and structures of the derivatized cytochromes are not significantly perturbed by the modifications ; neither are the ...
متن کاملFormation and inhibition of Nε-(carboxymethyl)lysine in saccharide-lysine model systems during microwave heating.
N(ε)-(carboxymethyl) lysine (CML) is the most abundant advanced glycation end product (AGE), and frequently selected as an AGEs marker in laboratory studies. In this paper, the formation and inhibition of N(ε)-(carboxymethyl)lysine in saccharide-lysine model systems during microwave heating have been studied. The microwave heating treatment significantly promoted the formation of CML during Mai...
متن کاملL-Ascorbic Acid Peroxidase
Euglena gracilis was found to contain a peroxidase that specifically requires L-ascorbic acid as the natural electron donor in the cytosol. The presence of an oxidation-reduction system metabolizing L-ascorbic acid was demonstrated in Euglena cells. Oxidation of L-ascorbic acid by the peroxidase, and the absence of ascorbic acid oxidase activity, suggests that the system functions to remove H20...
متن کاملL-Ascorbic acid degradation by bacteria. VIII. All the pathway in the L-ascorbic acid metabolism.
The medium used contained 3g of substrate, 150ml of 1/15M phosphate buffer and 150ml of sterile distilled water. 0.5g (dry weight) of the adapted cells was added to the medium and the whole was incubated at 30•‹ for 20 hours. For detecting the intermediate products, paper chromatography was chiefly used. For developing the nonvolatile acids, n-butanol-acetic acid-water (4:1:1) was used and the ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1983
ISSN: 0306-3283
DOI: 10.1042/bj2140289