SPONTANEOUS PUBERTAL DEVELOPMENT IN TURNER SYNDROME

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A New Case of Turner Syndrome with Early Pubertal Development

Turner syndrome (TS) is a relatively common chromosomal disorder caused by complete or partial X monosomy. The most frequently observed karyotype, 45, X, arises more often by loss of the paternal X or Y chromosome in meiosis or in early embryogenesis than by loss of the maternal X chromosome. The main clinical features of TS are short stature, gonadal dysgenesis, and not to undergo pubertal dev...

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Frequencies of spontaneous breast development and spontaneous menarche in Turner syndrome in Japan

The Growject® database on human GH treatment in Turner syndrome was analyzed in the Turner Syndrome Research Collaboration, and the relationships of the frequencies of spontaneous breast development and spontaneous menarche with karyotype and GH treatment were investigated. One hundred and three cases started GH treatment with 0.5 IU/kg/ week (0.5 IU group), and their dose was increased to 0.35...

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Spontaneous puberty in girls with early diagnosis of Turner syndrome.

OBJECTIVE To verify if the frequency of spontaneous pubertal development among girls with Turner syndrome (TS) diagnosed in infancy and childhood is greater than that of patients diagnosed later. SUBJECTS AND METHODS Thirty three girls aged < 10 years at the time of diagnosis were evaluated regarding pubertal development. The frequency of spontaneous puberty was compared with that of girls ag...

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Spontaneous carotid artery dissection in a patient with Turner syndrome.

noid hemorrhage (SAH). A neck CT angiography (CTA) showed marked narrowing of the right ICA distal to the bulb, with irregular and tapered appearance ( fig. 1 a, b) suggesting ICA dissection. Intracranial extension of the dissection was suspected due to the presence of SAH. A transesophageal echocardiogram revealed a dilated ascending aorta and no evidence of aortic dissection. The remainder of...

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Prediction of Pubertal Growth at Start of Estrogen Replacement Therapy in Turner Syndrome

In estrogen replacement therapy in Turner syndrome, there is no report which recommends the timing of the start of estrogen therapy in relation to height or adult height prediction. We have established a prediction model for pubertal growth (height difference from the start of estrogen therapy until adult height) at the start of estrogen replacement therapy. Twenty-seven Turner girls without sp...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1993

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-199305001-00514