Stability Constants of Uranyl Chelates with Nuclear-Substituted Salicylic Acids

The glycogenolytic activity of some substituted salicylic acids.

Determination of stability constant of some transition metal ions chelates with substituted pyrazoles

The stability constants of the complexes of Cu (II), Co (II) and Ni (II) ions with 3-(3’-nitrophenyl)4-(4"-chlorobenzoyl)-5-(2-hydroxyphenyl) pyrazole (L1), 3-(4’-chlorophenyl)-4-(4"-chlorobenzoyl)-5-(2hydroxyphenyl) pyrazole (L2), 3-(4’-methoxyphenyl)-4-benzoyl-5-(2-hydroxyphenyl) pyrazole (L3), 3(4-bromophenyl)-4-furoyl-5-(2-hydroxyphenyl) pyrazole (L4) have been determined by the pH-metric m...

Estimation of Stability Constants with Connectivity Index: Development of Bivariate and Multivariate Linear Models for Copper(II) Chelates with Oligopeptides

The equilibrium constants K1, Ka and β1 of 25 copper(II) complexes with di(N = 15), tri(N = 5), tetra(N = 2), and pentapeptides (N = 3) were estimated by using linear models based on the valence connectivity index of the 3 order (χ). For the stability constant K1 two kinds of models were developed: bivariate models, which divide a molecule into Nand C-terminal segments, and multivariate models,...

Phosphonated chelates for nuclear imaging.

A series of bis-, tris- and tetra-phosphonated pyridine ligands is presented. In view of their potential use as chelates for radiopharmaceutical applications, the physico-chemical properties of the ligands and of their Co(II), Ni(II), Cu(II), and Zn(II) complexes were studied by means of potentiometry and UV-Vis absorption spectroscopy. The pKa values of the ligands and of the complexes, as wel...

Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls.

Salicylic acids are shown to be readily available and versatile starting materials that easily undergo a tandem arylation-protodecarboxylation process under Pd-catalysis. The corresponding meta-arylphenols can subsequently be easily transformed into a variety of meta-functionalized biaryls, highlighting the versatility of this approach to access this structural motif.