Stable suppression of tumorigenicity by virus-mediated RNA interference
نویسندگان
چکیده
منابع مشابه
Stable suppression of tumorigenicity by virus-mediated RNA interference.
Most human tumors harbor multiple genetic alterations, including dominant mutant oncogenes. It is often not clear which of these oncogenes are continuously required and which, when inactivated, may inhibit tumorigenesis. Recently, we developed a vector that mediates suppression of gene expression through RNA interference. Here, we use a retroviral version of this vector to specifically and stab...
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2002
ISSN: 1535-6108
DOI: 10.1016/s1535-6108(02)00122-8