Standard operating procedure for optimal identification of mycobacteria using 16S rRNA gene sequences

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Standard operating procedure for optimal identification of mycobacteria using 16S rRNA gene sequences

Genetic sequencing is increasingly used for the identification of bacteria and for many of them, including mycobacteria, the analysis of the 16S rRNA gene represents the gold standard. Sequencing technology has greatly improved in recent years and now allows one to obtain good quality electropherograms also in non specialized settings. The interpretation of the electropherograms still lacks how...

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DNA sequencing by Microseq kit targeting 16S rRNA gene for species level identification of mycobacteria.

BACKGROUND & OBJECTIVES Identification of mycobacteria to the species level is of therapeutic significance. Conventional methods are laborious and time consuming so we did 16S rRNA sequencing using a commercial MicroSeq sequencing kit, which includes DNA sequencing with software package for identification and phylogenetic analysis of clinical mycobacterial isolates. METHODS A total of 47 myco...

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Pasteurella multocida is known as an important heterogenic bacterial agent causes some severe diseases such as fowl cholera in poultry and haemorrhagic septicaemia in cattle and buffalo. A polymerase chain reaction (PCR) assay was developed using primers derived from conserved part of 16S-23S rRNA gene. The PCR amplified a fragment size of 0.7 kb using DNA from nine avian P. multocida  isolates...

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A bacterial strain Bz02 was isolated from a water sample collected from river Gomti at the Indian city of Lucknow. We characterized the strain using 16S rRNA sequence. Phylogenetic analysis showed that the strain formed a monophyletic clade with members of the genus Comamonas. The closest phylogenetic relative was Comamonas testosteroni with 95% 16S rRNA gene sequence similarity. It is proposed...

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ژورنال

عنوان ژورنال: Standards in Genomic Sciences

سال: 2010

ISSN: 1944-3277

DOI: 10.4056/sigs.932152