Stem Cells and Tissue-Engineered Skin
نویسندگان
چکیده
منابع مشابه
Stem cells and tissue-engineered skin.
Advances in tissue engineering of skin are needed for clinical applications (as in wound healing and gene therapy) for cutaneous and systemic diseases. In this paper we review the use of epidermal stem cells as a source of cells to improve tissue-engineered skin. We discuss the importance and limitations of epidermal stem cell isolation using biomarkers, in quest of a pure stem cell preparation...
متن کاملConstruction of tissue engineered skin with human amniotic mesenchymal stem cells and human amniotic epithelial cells.
OBJECTIVE To establish a new model for construction of tissue engineered skin with human amniotic mesenchymal stem cells (hAMSCs) and human amniotic epithelial cells (hAECs). MATERIALS AND METHODS hAMSCs and hAECs were isolated from amniotic membrane. The morphology and phenotype of hAMSCs and hAECs were confirmed by microscope and flow cytometry, respectively. Then, we performed RT-PCR and i...
متن کاملSkin Stem Cells
The future development of medicine will greatly depend on research, knowledge and clinical application of stem cells. In recent years, stem cells especially; skin stem cells have been very interesting and amazing targets for study and scientific application in the following fields : 1- Cell-based therapy; 2- Regenerative medicine and tissue engineering; 3- Gene therapy; 4- Therapeutic cloning; ...
متن کاملThe Role of Biodegradable Engineered Nanofiber Scaffolds Seeded with Hair Follicle Stem Cells for Tissue Engineering
Background: The aim of this study was to fabricate the poly caprolactone (PCL) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (HFSC) in the graft material using electrospun PCL nanofiber scaffold for tissue engineering applications. Methods: The bulge region of rat whisker was isolated and cultured in DMEM: n...
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As specific stem cells of skin tissue, epidermal stem cells (ESCs) have been proved to be closely related to the wound repair. As a result, studying more targeted markers for a rapid acquisition of ESCs has become a hot issue for TES. For server burn wound or ulcer, the creation of ideal scaffold as matrix for cell proliferation and differentiation was needed for TES as useful ESCs being rare. ...
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ژورنال
عنوان ژورنال: Skin Pharmacology and Physiology
سال: 2009
ISSN: 1660-5535,1660-5527
DOI: 10.1159/000178864