Stepwise Neoplastic Transformation of a Telomerase Immortalized Fibroblast Cell Line
نویسندگان
چکیده
منابع مشابه
Stepwise neoplastic transformation of a telomerase immortalized fibroblast cell line.
We have described recently a human fibroblast cell line immortalized through ectopic telomerase expression (cen3tel), in which the extension of the life span was associated with the appearance of chromosomal aberrations and with the ability to grow in the absence of solid support. As reported in this article, on further propagation in culture, cen3tel cells became neoplastically transformed, be...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2005
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-05-1140