Steroid responsiveness and wheezing phenotypes
نویسندگان
چکیده
منابع مشابه
Steroid responsiveness and wheezing phenotypes.
Oral corticosteroids are the cornerstone of management of acute moderate or severe asthma whilst preventive inhaled corticosteroids are the mainstay of the preventive management of children with asthma. Yet, variation in the magnitude of response to corticosteroids has been observed. There is increasing evidence that preschool-aged children with viral-induced asthma may display a certain degree...
متن کاملWheezing phenotypes in childhood.
There can no longer be any doubt that, within the spectrum On this dubious basis, a third phenotype with a peak prevalence at six years was identified between the group of of wheezing disorders of childhood, several distinct phenoearly transient wheezers and later atopic asthmatic subjects. types can be recognised. Although clinicians have been The distinction between children who wheezed in th...
متن کاملPeak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood.
BACKGROUND There is increasing evidence that wheezing during childhood may be a heterogeneous condition, and that different forms of wheezing may be associated with different risk factors and prognosis. The aim of this study was to determine if measures of airway lability and of atopy could identify distinct wheezing phenotypes during childhood. METHOD In a cohort of children followed from bi...
متن کاملSpirometry and bronchodilator responsiveness in wheezing preschool children
Methods We carried out a retrospective analysis of incentive spirometry tests in recurrent wheezing children, aged 2-5 years, from our center, performed between September 2012 and March 2014. Lung function was assessed before and after 400 mg of inhaled salbutamol using a Jaeger spirometer v.4.65 (CareFusion). Wheezing symptoms, parental asthma, prematurity, passive smoking exposure, atopy and ...
متن کاملSteroid responsiveness in connective tissue diseases.
Thirty-four patients with connective tissue disease used dexamethasone drops 0.1% in one eye for 6 weeks. There was a higher incidence of positive steroid response than would be expected in a normal population. Most of the male patients were responders. Care should be exercised when prescribing local steroids for these patients. Males should be offered regular screening for glaucoma.
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ژورنال
عنوان ژورنال: Paediatric Respiratory Reviews
سال: 2011
ISSN: 1526-0542
DOI: 10.1016/j.prrv.2011.02.007