Stochastic processes constrain the within and between host evolution of influenza virus
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چکیده
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A stochastic model for the evolution of the influenza virus
Consider a birth and death chain to model the number of types of a given virus. Each type gives birth to a new type at rate λ and dies at rate 1. Each type is also assigned a fitness. When a death occurs either the least fit type dies (with probability 1 − r) or we kill a type at random (with probability r). We show that this random killing has a large effect (for any r > 0) on the behavior of ...
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ژورنال
عنوان ژورنال: eLife
سال: 2018
ISSN: 2050-084X
DOI: 10.7554/elife.35962