Stromal Cell-Derived Factor 1 Polymorphism in Retinal Vein Occlusion

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Stromal Cell-Derived Factor 1 Polymorphism in Retinal Vein Occlusion

BACKGROUND Stromal cell-derived factor 1 (SDF1) has crucial role in the regulation of angiogenesis and ocular neovascularisation (NV). The purpose of this study was to evaluate the association between SDF1-3'G(801)A polymorphism and NV complications of retinal vein occlusion (RVO). METHODS 130 patients with RVO (median age: 69.0, range 35-93 years; male/female- 58/72; 55 patients had central ...

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Sulfur Mustard Exposure and Non-Ischemic Central Retinal Vein Occlusion

A 41-year-old man was referred with a complaint of visual loss in his left eye and his best corrected visual acuity was 20/80. Slit lamp examination showed arborizing conjunctival vessels and dry eye. Fundus examination and fluorescein angiography revealed a non-ischemic central retinal vein occlusion. Cardiovascular, rheumatologic, and hematologic work up showed no abnormal findings. An ascert...

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Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.

Stromal cell-derived factor-1 (SDF-1) causes chemotaxis of CXCR4-expressing bone marrow-derived cells. SDF-1 is involved in the pathogenesis of various vascular diseases, including those of the eye. However, the role of SDF-1 in neuronal diseases is not completely understood. Here, we show higher SDF-1 levels in the vitreous humor of patients with retinal detachment (RD) compared with normal pa...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2016

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0166544