Structural analysis of bovine norovirus protruding domain

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Structural analysis of bovine norovirus protruding domain.

We determined a structure of a bovine (genogroup III, GIII) norovirus capsid protruding (P) domain using X-ray crystallography. The bovine P domain was reminiscent of other norovirus genogroups (GI, GII, GIV, and GV), but closely matched the human GI P domain. We also identified a monoclonal antibody that was capable of binding the five different (GI-GV) P domains. Our data suggests that geneti...

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ژورنال

عنوان ژورنال: Virology

سال: 2016

ISSN: 0042-6822

DOI: 10.1016/j.virol.2015.10.022