Structural and functional aspects of filamins
نویسندگان
چکیده
منابع مشابه
Structural and Functional Evaluation of C. elegans Filamins FLN-1 and FLN-2
Filamins are long, flexible, multi-domain proteins composed of an N-terminal actin-binding domain (ABD) followed by multiple immunoglobulin-like repeats (IgFLN). They function to organize and maintain the actin cytoskeleton, to provide scaffolds for signaling components, and to act as mechanical force sensors. In this study, we used transcript sequencing and homology modeling to characterize th...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
سال: 2001
ISSN: 0167-4889
DOI: 10.1016/s0167-4889(01)00072-6