Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes
نویسندگان
چکیده
منابع مشابه
Structural insights into RNA duplexes with multiple 2΄-5΄-linkages
2΄-5΄-linked RNAs play important roles in many biological systems. In addition, the mixture of 2΄-5΄ and 3΄-5΄ phosphodiester bonds have emerged as a plausible structural element in prebiotic RNAs. Toward our mechanistic studies of RNA folding and structures with heterogeneous backbones, we recently reported two crystal structures of a decamer RNA duplex containing two and six 2΄-5΄-linkages, s...
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ژورنال
عنوان ژورنال: ChemBioChem
سال: 2016
ISSN: 1439-4227
DOI: 10.1002/cbic.201600349