Structural neural networks subserving oculomotor function in first-episode schizophrenia
نویسندگان
چکیده
منابع مشابه
Structural neural networks subserving oculomotor function in first-episode schizophrenia.
BACKGROUND Smooth pursuit and antisaccade abnormalities are well documented in schizophrenia, but their neuropathological correlates remain unclear. METHODS In this study, we used statistical parametric mapping to investigate the relationship between oculomotor abnormalities and brain structure in a sample of first-episode schizophrenia patients (n = 27). In addition to conventional volumetri...
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BACKGROUND We tested the hypothesis that schizophrenia is primarily a frontostriatal disorder by examining executive function in first-episode patients. Previous studies have shown either equal decrements in many cognitive domains or specific deficits in memory. Such studies have grouped test results or have used few executive measures, thus, possibly losing information. We, therefore, measured...
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BACKGROUND A number of functional brain abnormalities have been reported in schizophrenia, but it remains to be determined which of them represent trait and state markers of the illness. AIMS To delineate regional brain dysfunctions that remain stable and those that fluctuate during the course of schizophrenia. METHOD A cohort of patients with first-episode schizophrenia and a matched group...
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Compromised neurocognition is a core feature of schizophrenia. Following Heinrichs and Zakzanis’s (1998) seminal meta-analysis of middle-aged and predominantly chronic schizophrenia samples, the aim of this study is to provide a meta-analysis of neurocognitive findings from 47 studies of first-episode (FE) schizophrenia published through October 2007. The meta-analysis uses 43 separate samples ...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 2004
ISSN: 0006-3223
DOI: 10.1016/j.biopsych.2004.08.017