Structural Requirements for Mutational Lutropin/Choriogonadotropin Receptor Activation
نویسندگان
چکیده
منابع مشابه
Structural requirements for mutational lutropin/choriogonadotropin receptor activation.
Different activation mechanisms of glycoprotein hormone receptors, which are members of the G protein-coupled receptor superfamily, have been proposed. For example, the large ectodomain of glycoprotein hormone receptors may function as an inverse agonist keeping the transmembrane domain in an inactive conformation. To provide support for this hypothesis, we have generated different lutropin/cho...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2002
ISSN: 0021-9258
DOI: 10.1074/jbc.m203491200