Structure-activity relationship in N3-alkyl-xanthine derivatives.
نویسندگان
چکیده
منابع مشابه
Structure-Activity Relationship of Xanthones as Inhibitors of Xanthine Oxidase.
Polygala plants contain a large number of xanthones with good physiological activities. In our previous work, 18 xanthones were isolated from Polygala crotalarioides. Extented study of the chemical composition of the other species Polygala sibirica led to the separation of two new xanthones-3-hydroxy-1,2,6,7,8-pentamethoxy xanthone (A) and 6-O-β-d-glucopyranosyl-1,7-dimethoxy xanthone (C)-toget...
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Silybin or silibinin, a flavonolignan isolated from Milk thistle seeds, is one of the popular dietary supplements and has been extensively studied for its antioxidant, hepatoprotective and anti-cancer properties. We have envisioned that potency of silybin could be further enhanced through suitable modification/s in its chemical structure. Accordingly, here, we synthesized and characterized a se...
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ژورنال
عنوان ژورنال: The Japanese Journal of Pharmacology
سال: 1988
ISSN: 0021-5198,1347-3506
DOI: 10.1254/jjp.46.373