Studies of N-Acyl-2-pyridinecarboxanilides. Preparation by Various Reaction Sequences and Reaction with Hydrogen Chloride to give Acyl Imidate Hydrochlorides through an Intramolecular N -> O Acyl Migration.
نویسندگان
چکیده
منابع مشابه
Synthesis, Characterization and Antibacterial Activity Studies of Some N-Acyl-N'-aryl Thiourea Derivatives
Some N¬-acyl-N'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. The structures of synthesized compounds have been characterized by IR, 1HNMR spectral studies. The synthesized compounds 5(a-f) have been screened for antibacterial activity. The effect of the structure of the investigated compounds on the antibacterial activ...
متن کاملsynthesis, characterization and antibacterial activity studies of some n-acyl-n'-aryl thiourea derivatives
some n¬-acyl-n'-aryl thiourea derivatives 4(a-f) have been prepared by the reaction of acyl halides ammonium thiocyanate and aryl amines. the structures of synthesized compounds have been characterized by ir, 1hnmr spectral studies. the synthesized compounds 5(a-f) have been screened for antibacterial activity. the effect of the structure of the investigated compounds on the antibacterial activ...
متن کاملInsertion of an alkene into an ester: intramolecular oxyacylation reaction of alkenes through acyl C-O bond activation.
lation” could be an alternative to the aldol reaction. Atom economy and ester manipulation, however, are rarely compatible: esters usually fragment after reactions with nucleophiles, or decarbonylate when activated with transition metals. In the rare cases when the acyl C O bond is activated and decarbonylation is suppressed, the acyl metal alkoxide complexes can undergo additional transformati...
متن کاملN-acyl glycinates as acyl donors in serine protease-catalyzed kinetic resolution of amines. Improvement of selectivity and reaction rate.
Enzymatic kinetic resolution of aliphatic and benzylic amines leading to (S)-amides was achieved by using alkaline protease as the catalyst and N-octanoyl glycine trifluoroethyl ester as the acyl donor; enantioselectivity ranged between 4 to 244, while reaction times were dramatically shortened and ranged between 15 min to 6 h.
متن کاملNative N-glycopeptide thioester synthesis through N→S acyl transfer
Peptide thioesters are important tools for the total synthesis of proteins using native chemical ligation (NCL). Preparation of glycopeptide thioesters, that enable the assembly of homogeneously glycosylated proteins, is complicated by the perceived fragile nature of the sugar moiety. Herein, we demonstrate the compatibility of thioester formation via N→S acyl transfer with native N-glycopeptid...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1980
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.34b-0313