STUDIES OF UREA EXCRETION. IX. COMPARISON OF UREA CLEARANCES CALCULATED FROM THE EXCRETION OF UREA, OF UREA PLUS AMMONIA, AND OF NITROGEN DETERMINABLE BY HYPOBROMITE
نویسندگان
چکیده
منابع مشابه
Studies of Urea Excretion. Ix. Comparison of Urea Clearances Calculated from the Excretion of Urea, of Urea plus Ammonia, and of Nitrogen Determinable by Hypobromite.
According to the usually accepted concept, the urea removed from the blood by the kidneys is excreted in two forms, chiefly as urea itself, but partly as ammonia. That the ammonia of the urine is formed in the kidneys was demonstrated by Nash and Benedict (1921), in work which has been confirmed by other authors (cf. Peters and Van Slyke, I, p. 373). Evidence from animal experiments in v4vo has...
متن کاملMechanism of Urea Excretion
1. Urea is present in the cells of the proximal convoluted tubule in a concentration higher than that of the blood or than that of the cells of any of the other kidney tubules. 2. Such a condition can only be reconciled to an assumption of an active secretion (excretion) on the part of these cells. 3. Urea also passes through the glomerular filter with the other crystalloids of the blood plasma...
متن کاملUrea Excretion at Low Urine Volumes. the Calculation of "minimal" Urea Clearances.
In a previous paper (1), it was shown that the calculation of standard urea clearances from urine volumes of less than about 0.35 ml. per minute gives results which are considerably too low. It was found that the lower the urine volume is, the greater the error becomes, as the calculated standard clearance falls lower and lower. This was demonstrated in 173 adults, including patients with toxem...
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Plasma urea and creatinine concentrations and urea and creatinine clearances and excretion were measured in a sample of 40 infants of 25*5-33 weeks' gestation, birth weight 720-2000 g, between the ages of 0 5 and 33 days. Creatinine excretion rate was between 60 and 120 gmol/kg/day in the first five postnatal weeks (mean 90.5) and was independent of sex or growth retardation. This can be used i...
متن کاملThe Comparison of Urea with Urea + Ammonia Clearances in Acidotic Dogs.
In 1921 Nash and Benedict (11) advanced the hypothesis that urinary ammonia is formed in the kidney from some precursor in the blood. This conclusion was based upon the observation that the concentration of ammonia was higher in the renal vein than in the renal artery, that the quantity of ammonia in arterial blood was too small to supply the ammonia found in the urine, and that the arterial am...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1935
ISSN: 0021-9738
DOI: 10.1172/jci100740