Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
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چکیده
منابع مشابه
Studies on the catalytic domains of multiple JmjC oxygenases using peptide substrates
The JmjC-domain-containing 2-oxoglutarate-dependent oxygenases catalyze protein hydroxylation and N(ϵ)-methyllysine demethylation via hydroxylation. A subgroup of this family, the JmjC lysine demethylases (JmjC KDMs) are involved in histone modifications at multiple sites. There are conflicting reports as to the substrate selectivity of some JmjC oxygenases with respect to KDM activities. In th...
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ژورنال
عنوان ژورنال: Epigenetics
سال: 2014
ISSN: 1559-2294,1559-2308
DOI: 10.4161/15592294.2014.983381