Suicidal Behaviours in Affective Disorders: A Defcit of Cognitive Inhibition?

Suicidal Behaviours in LGBT Populations

Disorders of cognitive and affective development in cerebellar malformations.

Acquired cerebellar lesions in adults and children can lead to the development of a complex behavioural pattern termed 'Cerebellar Cognitive Affective Syndrome' (Schmahmann and Sherman, Brain, 1998; 121: 561-79), which is characterized by reduced cognitive efficiency associated with specific neuropsychological deficits (executive and visuospatial disorders), expressive language disorders (mild ...

A systematic review of cognitive remediation for schizo-affective and affective disorders.

BACKGROUND Cognitive remediation is accepted as an important therapeutic intervention in schizophrenia, but few studies provide data on whether the benefits extend to affective disorders. OBJECTIVES To review quantitatively studies of cognitive remediation with samples that included cases of schizoaffective disorder, affective psychosis, unipolar and/or bipolar disorders. METHODS Twenty one...

MicroRNAs: fundamental regulators of gene expression in major affective disorders and suicidal behavior?

1 Department of Neurosciences, Mental Health and Sensory Organs – Sant’Andrea Hospital, Sapienza University of Rome, Rome, Italy 2 Department of Neurosciences, Ohio State University, Columbus, OH, USA 3 Department of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA 4 Section of Psychiatry, Department of Neuroscience, Rehabilitation, Ophthalmology,...

Modeling psychotic and cognitive symptoms of affective disorders: Disrupted latent inhibition and reversal learning deficits in highly stress reactive mice.

Increased stress reactivity has repeatedly been reported in patients suffering from psychiatric diseases including schizophrenia and major depression. These disorders also have other symptoms in common, such as cognitive deficits and psychotic-like behavior. We have therefore investigated if increased stress reactivity is associated with these phenotypic endpoints in an animal model of affectiv...