Superior T memory stem cell persistence supports long-lived T cell memory

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Superior T memory stem cell persistence supports long-lived T cell memory.

Long-lived memory T cells are able to persist in the host in the absence of antigen; however, the mechanism by which they are maintained is not well understood. Recently, a subset of human T cells, stem cell memory T cells (TSCM cells), was shown to be self-renewing and multipotent, thereby providing a potential reservoir for T cell memory throughout life. However, their in vivo dynamics and ho...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2013

ISSN: 0021-9738

DOI: 10.1172/jci66327