Supermolecular design: From molecules to solid states

Solid supported lipid bilayers: From biophysical studies to sensor design

The lipid bilayer is one of the most eloquent and important self-assembled structures in nature. It not only provides a protective container for cells and sub-cellular compartments, but also hosts much of the machinery for cellular communication and transport across the cell membrane. Solid supported lipid bilayers provide an excellent model system for studying the surface chemistry of the cell...

Solid forms of pharmaceutical molecules

A drug discovery is characterized by two stages. The first in terms of time is called „lead structure“, followed by a so called „drug candidate“ stage. The lead structure stage involves selecting the optimum molecule of the pharmaceutical, while drug candidate stage means selecting the optimum solid form. Usually, 5 – 10 candidates pass to the drug candidate stage and the result is the selectio...

Probing weak non-covalent interactions in solution and solid states with designed molecules.

Selective examples of OH...arene, NH2...arene and C-HN[triple bond, length as m-dash]C weak interactions are presented using a flexible dibenzobicyclo[3.2.2]nonane scaffold for detection and comparative characterisation of non-covalent interactions in solution and solid states.

From Molecules to Morphology

From Molecules to Organisms

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