Supramolecular encapsulation of benzocaine and its metabolite para-aminobenzoic acid by cucurbit[7]uril
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منابع مشابه
Para-aminobenzoic Acid Production by Staphylococci
1. Strains of staphylococci produce diazotizable materials which can be converted to a dye, and the intensity of the color reaction can be quantitated in the same manner as p-aminobenzoic acid. The sulfonamide-resistant strains which we have studied produce more diazotizable substance than non-resistant strains. 2. The development of a color by the diazotizable substance can be inhibited by exp...
متن کاملThe Isolation and Identification of Para-aminobenzoic Acid Produced by Staphylococci Resistant to Sulfonamide
Previous studies have shown that when Staphylococcus aureus becomes resistant to sulfonamides, an antisulfonamide substance is produced in the growth medium. Although these studies suggested that the substance was p-aminobenzoic acid (PABA), isolation and positive identification were not achieved. Because of the importance of these observations, unequivocal identification of the product was att...
متن کاملINHIBITION OF ESCHERICHIA COLI BY p-AMINOBENZOIC ACID AND ITS REVERSAL BY p-HYDROXYBENZOIC ACID
p-Aminobenzoic acid (PABA) exerts three metabolic effects on E. coli: it acts as a normal vitamin at low concentrations, as a source of another vitamin, p-hydroxybenzoic acid (POB), at moderate concentrations, and as a growth inhibitor at high concentrations (150 to 1600 microg./ml.). The inhibition is competitively reversed by POB in 1/100 the concentration of PABA. The inhibition is also reve...
متن کاملThe replacement of para-aminobenzoic acid by methionine in the growth of a Neurospora mutant.
Present knowledge of the function of para-aminobenzoic acid (PABA) has been derived almost exclusively from sulfanilamide (SAN) inhibition studies. Shive and Roberts (1946) have advanced the hypothesis that PABA is catalytically active in the synthesis of a number of metabolic products in Escherichia coli and that the enzyme systems concerned in their production are differentially sensitive to ...
متن کاملObservations on the Inhibition of Sulfonamide Action by Para-aminobenzoic Acid.
Considerable interest has been aroused recently in the investigation of substances which inhibit the action of the sulfonamide drugs. Lockwood (1) showed that peptones inhibit the action of sulfanilamide on streptococci. Stamp (2) isolated certain fractions of streptococci, and Green (3) isolated fractions of brucella, which have similar activity with respect to the corresponding organisms. Wes...
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ژورنال
عنوان ژورنال: New Journal of Chemistry
سال: 2016
ISSN: 1144-0546,1369-9261
DOI: 10.1039/c5nj03259h