Surface Modification of Titanium by Femtosecond Laser in Reducing Bacterial Colonization

In the past few decades, titanium and its alloys have been widely used in orthopaedic field. However, because is bioinert lacks antibacterial properties, infection may happen when bacteria attach to implant surfaces form biofilms. It has studied that some naturally existing micron-scale topographies can reduce bacterial attachment such as cicada wings gecko skins. The aim of this vitro study was find an with good biocompatibility antimicrobial properties by modification topographies. paper, a femtosecond laser provide microtopography coatings on Ti substrates. surface morphology substrates observed scanning electron microscopy (SEM). XPS fulfil chemical compositional analysis. wettability measured contact angle measurement system. effect different microstructures activities bone marrow mesenchymal stem cells (BMSC) functions investigated. results revealed restrain adhesion Staphylococcus aureus (S. aureus) epidermidis epidermidis), which are common pathogens infections. addition, stimulated BMSC proliferation. Our studies suggest microtopography-coated sample modified showed promising favourable biocompatibility. technique provides accurate valid way produce outstanding could be modify metal implants great potential.