Survey of genomic repeat sequence-PCRs that detect differences between inbred mouse strains
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چکیده
منابع مشابه
Digit ratio (2D:4D) and behavioral differences between inbred mouse strains.
Digit ratio (2D:4D) is a trait, which is sexually differentiated in a variety of species. In humans, males typically have shorter second digits (2Ds) (index fingers) compared to fourth digits (4Ds) (ring fingers) whereas females' fingers are more equal in length. Smaller, more masculine, digit ratios are thought to be associated with higher prenatal testosterone levels, greater sensitivity to p...
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The Illumina Infinium MethylationEPIC provides an efficient platform for profiling DNA methylation in humans at over 850,000 CpGs. Model organisms such as mice do not currently benefit from an equivalent array. Here we used this array to measure DNA methylation in mice. We defined probes targeting conserved regions and performed differential methylation analysis and compared between the array-b...
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Forty-four inbred and four randombred rat strains and 20 inbred mouse strains were examined for their Ah phenotype by determining the induction of liver microsomal aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity (EC 1.14.14.1) by intraperitoneal treatment with either beta-naphthoflavone or 3-methylcholanthrene. All 48 rat strains were found to be Ah-responsive. The maximally induced hydr...
متن کاملOrigin of inbred NZ mouse strains.
Inbreeding of mice was begun in 1948 in our labora tories in response to the request of Dr. Franz Bielschow sky, who recognized the need for genetically and nutri tionally uniform animals for cancer research. The resulting strains of inbred NZ mice proved useful for research in immunology, biochemistry, and other fields, and they have been widely distributed. We often have inquiries from invest...
متن کاملGlucuronidase phenotypes of inbred mouse strains.
M A M M A L I A N ,&glucuronidase has been relatively well characterized with regard to such parameters as substrate specificity, tissue levels, pH dependence, intracellular localization, and protein structure. For a recent review the reader may consult LEVVY and CONCHIE (1966). Although this information failed to elucidate the physiolcigical role of glucuronidase, it has provided a convenient ...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 1995
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672300033164