Survival and drug discontinuation analyses in a large cohort of methotrexate treated rheumatoid arthritis patients.
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چکیده
منابع مشابه
Survival and drug discontinuation analyses in a large cohort of methotrexate treated rheumatoid arthritis patients.
OBJECTIVES To determine the probability of drug continuation in a large cohort of methotrexate treated rheumatoid arthritis (RA) patients, the reasons for discontinuation of methotrexate, the overall survival of the members of this cohort, and the causes of death in these patients. METHODS Yearly follow up was conducted in methotrexate treated RA patients who formed a cohort between 1981 and ...
متن کاملLiver Toxicity in Rheumatoid Arthritis Patients Treated With Methotrexate
Background:Methotrexate (MTX) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (RA) which can be associated with toxic effects on different organs. This study was designed to investigate the hepatotoxic effects in RA patients treated with MTX. Methods: In this cross-sectional observational study, RA patients who received standard d...
متن کاملliver toxicity in rheumatoid arthritis patients treated with methotrexate
background:methotrexate (mtx) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (ra) which can be associated with toxic effects on different organs. this study was designed to investigate the hepatotoxic effects in ra patients treated with mtx. methods: in this cross-sectional observational study, ra patients who received standard do...
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OBJECTIVE To investigate the frequency of remaining pain in early rheumatoid arthritis (RA) after 3 months of treatment with methotrexate as the only disease modifying antirheumatic drug, with a special focus on patients with a good clinical response. METHODS The study base was cases reported to a population-based early RA cohort who had followup data from the Swedish Rheumatology Quality Reg...
متن کاملPurine enzymes in patients with rheumatoid arthritis treated with methotrexate.
OBJECTIVES To study (a) purine metabolism during treatment with methotrexate (MTX) in patients with rheumatoid arthritis (RA) and (b) the relation of purine metabolism with efficacy and toxicity of MTX treatment. METHODS One hundred and three patients with active RA who started treatment with MTX were included. The initial MTX dosage was 7.5 mg/week and raised to a maximum of 25 mg weekly if ...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1995
ISSN: 0003-4967
DOI: 10.1136/ard.54.9.708