Switching renal transplant recipients to belatacept therapy: results of a real-life gradual conversion protocol
نویسندگان
چکیده
منابع مشابه
Belatacept conversion in African American kidney transplant recipients with severe renal dysfunction
OBJECTIVES Conversion from calcineurin inhibitor-based maintenance immunosuppression to belatacept in kidney transplant recipients has been demonstrated to improve renal function while maintaining efficacy against rejection. However, conversion studies to date have excluded patients with an estimated glomerular filtration rate < 35 mL/min/1.73 m2. METHODS We describe two patients with an esti...
متن کاملSwitching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study.
BACKGROUND AND OBJECTIVES Prolonged use of calcineurin inhibitors (CNIs) in kidney transplant recipients is associated with renal and nonrenal toxicity and an increase in cardiovascular risk factors. Belatacept-based regimens may provide a treatment option for patients who switch from CNI-based maintenance immunosuppression. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This is a randomized, ...
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ABSTRACT Background: Correction of the uremic state by a functioning allograft often restores fertility in women of reproductive age. The rate of fertility significantly differs between industrial countries, developing and middle east countries. On the other hand the results of pregnancy in Kidney Transplantation (KTP) patients are significantly better than hemodialysis patients, and pregnancy...
متن کاملQuantitative Analysis of CMV-DNA Load in Renal Transplant Recipients Using Real-Time PCR
No abstract
متن کاملHistopathologic evaluation of Verrucous skin lesions in renal transplant recipients
Background: Warts are common in renal allograft recipients (RAR) with reported incidence of 24% to 100%. These patients also demonstrate an accelerated malignant transformation of warts. Although in immunocompetent patients, the histology of common warts is quite predictable, this is not so in RAR. Objective: The purpose of this study was to evaluate the histopathologic findings of warty lesion...
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ژورنال
عنوان ژورنال: Transplant Immunology
سال: 2019
ISSN: 0966-3274
DOI: 10.1016/j.trim.2019.04.002