Synergetic effects of doxycycline-loaded chitosan nanoparticles for improving drug delivery and efficacy

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Synergetic effects of doxycycline-loaded chitosan nanoparticles for improving drug delivery and efficacy

INTRODUCTION Doxycycline, a broad-spectrum antibiotic, is the most commonly prescribed antibiotic worldwide for treating infectious diseases. It may be delivered orally or intravenously but can lead to gastrointestinal irritation and local inflammation. For treatment of uterine infections, transcervical administration of doxycycline encapsulated in nanoparticles made of biodegradable chitosan m...

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ژورنال

عنوان ژورنال: International Journal of Nanomedicine

سال: 2012

ISSN: 1178-2013

DOI: 10.2147/ijn.s27328