Synthesis of 2-Substituted 9, 10-Dihydro-8 H-benzo [4, 5] cyclohepta [d] thiazole Derivatives

Synthesis and Antimicrobial Evaluation of Novel Substituted Acetamido-4-subtituted-thiazole-5-indazole Derivatives

A series of novel molecules containing thiazole and indazole ring structure were designed and synthesized. The compounds are synthesized on gram scale by using series of reactions having vicarious reaction and coupling reactions. We have optimized all the reaction steps for getting good yields. For first time we have synthesized substituted indazole acetic acid which is coupled with different s...

Synthesis Of 2-[4-(Substituted Benzylidene)-5-Oxo-4,5-Dihydro-Oxazol-2-Ylmethyl]-Isoindole-1,3-Dione Derivatives as Novel Potential Antimicrobial Agents

In the present study, a series of new substituted oxazolone derivatives (4a-4h) were synthesized by the Erlenmeyer condensation of phthaloylglycylglycine with different aldehydes in the presence of anhydrous sodium acetate and acetic anhydride. The structure of newly-synthesized compounds were evaluated by elemental analyses and spectral ( UV-Visible, IR, NMR, Mass) studies. All the synthe...

Synthesis and Ab Initio/DFT Studies on 2-(4-methoxyphenyl)benzo[d]thiazole

2-aminothiophenol and 4-methoxybenzaldehyde were cyclized under microwave irridation and solvent free conditions to synthesize 2-(4-methoxyphenyl)benzo[d]thiazole. The molecular structure and vibrational frequencies of the title compound in the ground state have been investigated with ab initio (HF) and density functional theory methods (BLYP, B3LYP, B3PW91 and mPW1PW91) implementing the standa...

Synthesis , characterization and antimicrobial & antioxidant activity of 2 - Isonicotinoyl - 5 - methyl - 2 , 4 - dihydro - 3 H - pyrazolone derivatives

Synthesis of new polyurethanes based on 5, 6, 7, 8 – tetrabromo – 2, 3 – dihydro – 1, 4 – phthalazine dione

In this work, 5,6,7,8-Tetrabromo-2,3-dihydro-2,3-bis(2-hydroxyethyl)phthalazine-1,4-dione is synthesized by the reaction of 5,6,7,8-tetrabromo-2,3-dihydrophthalazine-1,4-dione with 2-bromoethanol in the presence of triethylamine. The obtained monomer was polymerized with different diisocyanates, including hexamethylenediisocyanate (HMDI), tolylene-2,4-diisocyanate (TDI), isophoronediisocyanate ...