Synthesis of a B/C trans-fused Morphine Structure
نویسندگان
چکیده
منابع مشابه
A 3,4-trans-Fused Cyclic Protecting Group Facilitates a-Selective Catalytic Synthesis of 2-Deoxyglycosides**
A practical approach has been developed to convert glucals and rhamnals into disaccharides or glycoconjugates with high a-selectivity and yields (77–97%) using a trans-fused cyclic 3,4-O-disiloxane protecting group and TsOH·H2O (1 mol%) as a catalyst. Control of the anomeric selectivity arises from conformational locking of the intermediate oxacarbenium cation. Glucals outperform rhamnals becau...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1965
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.13.1422