Synthesis of Xanthene Derivatives having Antispasmodic Action. VIII. Derivatives of 1-Chlorothioxanthene
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DABCO Catalyzed Synthesis of Xanthene Derivatives in Aqueous Media
The reaction of 5,5-dimethylcyclohexane-1,3-dione with various heteroarylaldehydes afforded the corresponding heteroaryl substituted xanthene derivatives 1(a-f). The reaction proceeds via the initial Knoevenagel, subsequent Michael, and final heterocyclization reactions using 1,4-diazabicyclo[2.2.2]octane (DABCO) as a catalyst in aqueous media. The synthesized heteroaryl substituted xanthenes 1...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1972
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.92.11_1386