Synthetic psychoactive cathinones: hypothermia and reduced lethality compared to methamphetamine and methylenedioxymethamphetamine
نویسندگان
چکیده
منابع مشابه
Synthetic Cannabinoids and Cathinones: Prevalence and Markets.
Over the past few years, the phenomenon of new designer drugs has attracted much attention. Synthetic cannabinoids and cathinones are the two main classes of these drugs. Both are potent drugs of abuse, and several cases of severe toxicity and deaths are reported. The present work is based on a systematic review of studies that have assessed the market and prevalence of synthetic cannabinoids a...
متن کاملOxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6.
Methamphetamine (MeAmp) abuse has recently experienced a resurgence and approaches to the treatment of its addiction similar to those used with cocaine have been considered. As the treatment regimes are likely to use drugs whose metabolism is related to that of MeAmp, studies were initiated to establish the enzymology of the fate of MeAmp. This report describes investigations of the role of CYP...
متن کاملSynthetic Cathinones: A New Public Health Problem
New psychoactive substances (NPS) have completely modified the drug scene and the current landscape of addiction. Synthetic substances, such as substituted or synthetic cathinones, also known as « legal highs », are often produced and used to mimic the effects of controlled drugs such as cocaine, methylenedioxymethamphetamine (MDMA, ecstasy), and methamphetamine. The overwhelming majority of sy...
متن کاملSynthesis and spectroscopic characterization of emerging synthetic cannabinoids and cathinones
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متن کاملEcstasy (3, 4-methylenedioxy-methamphetamine) (MDMA) (also called Adam, E, X, eccie) is a synthetic, psychoactive drug with both stimulant and hallucinogenic properties similar to methamphetamine and mescaline
Adverse Effects Common adverse physical effects of MDMA include agitation, anxiety, tachycardia and hypertension; more serious adverse reactions include hyperthermia, rhabdomyolysis, disseminated intravascular coagulation, renal failure, cardiac complications, intracranial hemorrhage, and hepatotoxicity [1, 2, 3]. Another term used to describe these adverse effects is “serotonin syndrome,” whic...
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ژورنال
عنوان ژورنال: Pharmacology Biochemistry and Behavior
سال: 2020
ISSN: 0091-3057
DOI: 10.1016/j.pbb.2020.172871