Synthetic Studies Towards the Partial Ergot Alkaloid LY228729, a Potent 5HT1a Receptor Agonist
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چکیده
منابع مشابه
Identification of a potent and selective synthetic agonist at the CRTH2 receptor.
The chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) is a G protein-coupled receptor whose function in vivo has been incompletely characterized. One of the reasons is that its current known ligands, prostaglandin D(2) and some of its metabolites, have either poor selectivity for CRTH2 or are metabolically unstable in vivo. In this study, we describe the bi...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 1998
ISSN: 0022-3263,1520-6904
DOI: 10.1021/jo9840022