Systemic absorption of Soframycin after subconjunctival injection.

Systemic absorption of Soframycin after subconjunctival injection.

Unusual complication associated with a subconjunctival injection of Soframycin.

Systemic absorption of topical and subconjunctival gentamicin.

Ten patients received ocular gentamicin therapy topically or subconjunctivally. Systemic absorption was not detected after topical use but was detected after subconjuctival administration. The relative safety of ocular gentamicin therapy is discussed and the literature is reviewed.

Subconjunctival administration of soframycin in the treatment of corneal infections.

THE properties of Soframycin, an antibiotic extracted from the mould Streptomyces decaris, were first evaluated by Massenat-Derouche (1954). Its properties in relation to the eye and its effect upon experimentally produced corneal infections were described by Ainslie and Henderson (1958). It was found to be especially effective against staphylococcal infections but was active too against many G...

Administering a subconjunctival injection

• Position the patient lying comfortably with his/her head supported on a pillow. • Reassure the patient that adequate anaesthetic drops will be instilled before the injection is given. • Instill anaesthetic drops at five-minute intervals over half an hour – a minimum of six drops. • Away from the patient’s view, draw up the prescribed medication using the 21G needle (Figure 1). • Change to the...