Systemic but not local rehydration restores dehydration-induced changes in pulmonary function in healthy adults

This study demonstrates that, in healthy adults, mild systemic dehydration induced by exercise the heat or a prolonged period of fluid restriction leads to negative alterations pulmonary function, primarily localized small airways. Oral rehydration, but not nebulized isotonic saline, is able restore function dehydrated individuals. Our findings highlight importance maintaining an adequate balance preserve function.