Systemic Inflammation, Adipose Tissue Tumor Necrosis Factor, and Leptin Expression
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چکیده
منابع مشابه
Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance.
Adipose tissue expresses tumor necrosis factor (TNF) and interleukin (IL)-6, which may cause obesity-related insulin resistance. We measured TNF and IL-6 expression in the adipose tissue of 50 lean and obese subjects without diabetes. Insulin sensitivity (S(I)) was determined by an intravenous glucose tolerance test with minimal-model analysis. When lean [body mass index (BMI) <25 kg/m(2)] and ...
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Gokhan S. Hotamisligil, * Peter Arner, Jose F. Caro, Richard L. Atkinson,11 and Bruce M. Spiegelman *Dana Farber Cancer Institute and Department of Cell Biology Harvard Medical School, Boston, Massachusetts 02115; *Karolinska Institute, Department of Medicine Huddinge University Hospital S-141 86 Huddinge, Sweden; 'Jefferson Medical College, Department of Medicine, Philadelphia, Pennsylvania 19...
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ژورنال
عنوان ژورنال: Obesity Research
سال: 2003
ISSN: 1071-7323
DOI: 10.1038/oby.2003.74