Systems Modeling Identifies Divergent Receptor Tyrosine Kinase Reprogramming to MAPK Pathway Inhibition
نویسندگان
چکیده
منابع مشابه
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway.
The MAPK (mitogen-activated protein kinase) pathway is one of the most important and intensively studied signalling pathways. It is at the heart of a molecular-signalling network that governs the growth, proliferation, differentiation and survival of many, if not all, cell types. It is de-regulated in various diseases, ranging from cancer to immunological, inflammatory and degenerative syndrome...
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ژورنال
عنوان ژورنال: Cellular and Molecular Bioengineering
سال: 2018
ISSN: 1865-5025,1865-5033
DOI: 10.1007/s12195-018-0542-y