T-Lineage Lymphoblastic Lymphoma and Leukemia—a MASSive Problem
نویسندگان
چکیده
منابع مشابه
T-lymphoblastic leukemia/lymphoma.
OBJECTIVES To review important concepts from the 2013 Society for Hematopathology/European Association for Haematopathology Workshop session on T-acute lymphoblastic leukemia/T-lymphoblastic lymphoma (T-ALL/T-LBL). METHODS Twenty-one submitted cases are reviewed and summarized, with emphasis on key diagnostic or biologic points, and supplemented with relevant literature citations. RESULTS E...
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T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LL) are neoplasias of immature T-cell precursors considered as a unique biological entity in the 2008 World Health Organization Classification of Hematologic Neoplasias1. Both entities are arbitrarily separated by a cut-off point of 20%-25% of blast cells in the bone marrow. There is a general agreement that T-ALL ...
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The bcr-abl rearrangement in T-lineage ALL has been rarely described. In the last three years we studied all new patients with ALL at diagnosis by cytogenetic and molecular analysis. Three out of eleven T-lineage ALL patients presented the rearrangement and only one was Philadelphia positive.
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ژورنال
عنوان ژورنال: Cancer Cell
سال: 2010
ISSN: 1535-6108
DOI: 10.1016/j.ccr.2010.10.003