Tamoxifen and Ovarian Function

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Tamoxifen and Ovarian Function

BACKGROUND Some studies suggest that the clinical parameter "amenorrhea" is insufficient to define the menopausal status of women treated with chemotherapy or tamoxifen. In this study, we investigated and compared the ovarian function defined either by clinical or biological parameters in pre-menopausal breast cancer patients treated with tamoxifen administered as adjuvant therapy. MATERIALS ...

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The Effect of Tamoxifen on the Fetal and Neonatal Ovarian Follicles Development in Rats

Objective(s) The effect of tamoxifen as a selective estrogen receptor modulator which is widely used for treatment of early and metastatic breast cancer was investigated on the folliculogenesis in rat's fetuses and neonates. Materials and Methods The pregnant rats assigned into test and control groups. Control group received olive oil and treatment groups received either 17-β-estradiol (10 µ...

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Evaluation of ovarian cysts in breast cancer cases on tamoxifen.

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0066616