Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region
نویسندگان
چکیده
منابع مشابه
Tandem duplication/triplication correlated with poly-cytosine stretch variation in human mitochondrial DNA D-loop region.
Somatic mutations in the mitochondrial DNA (mtDNA) displacement loop (D-loop) region have been frequently detected in various human cancers. In a previous study, we identified a polyplasmic 260-bp tandem duplication and triplication mutation in the mtDNA D-loop of one gastric cancer. In the present study, we adopted a more sensitive back-to-back polymerase chain reaction method to screen for th...
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ژورنال
عنوان ژورنال: Mutagenesis
سال: 2008
ISSN: 0267-8357,1464-3804
DOI: 10.1093/mutage/gen002