Targeted Drug Delivery and Treatment of Endoparasites with Biocompatible Particles of pH-Responsive Structure

etiology, significance, diagnosis and treatment of bruxiam

چکیده ندارد.

pH-Responsive nanoparticles for drug delivery.

First-generation nanoparticles (NPs) have been clinically translated as pharmaceutical drug delivery carriers for their ability to improve on drug tolerability, circulation half-life, and efficacy. Toward the development of the next-generation NPs, researchers have designed novel multifunctional platforms for sustained release, molecular targeting, and environmental responsiveness. This review ...

Targeted Delivery of siRNA with pH-Responsive Hybrid Gold Nanostars for Cancer Treatment

In this work, we report the engineering of gold nanostars (GNS) to deliver small interfering RNA (siRNA) into HepG2 cells. The ligand DG-PEG-Lipoic acid (LA)-Lys-9R (hydrazone) was designed to functionalize GNS, and create the nanoparticles named as 9R/DG-GNS (hydrazone). In the ligand, 2-deoxyglucose (DG) is the targeting molecule, polyethylene glycol (PEG) helps to improve the dispersity and ...

Nanoparticles for targeted, pH-responsive delivery of anti-biofilm drugs

85 ©2014 Society for Biomaterials

Advances in Targeted Drug Delivery