Targeted metagenomics of active microbial populations with stable-isotope probing
نویسندگان
چکیده
منابع مشابه
Targeted metagenomics of active microbial populations with stable-isotope probing.
The ability to explore microbial diversity and function has been enhanced by novel experimental and computational tools. The incorporation of stable isotopes into microbial biomass enables the recovery of labeled nucleic acids from active microorganisms, despite their initial abundance and culturability. Combining stable-isotope probing (SIP) with metagenomics provides access to genomes from mi...
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The application of metagenomics, the culture-independent capture and subsequent analysis of genomic DNA from the environment, has greatly expanded our knowledge of the diversity of microbes and microbial protein families; however, the metabolic functions of many microorganisms remain largely unknown. DNA stable-isotope probing (DNA-SIP) is a recently developed method in which the incorporation ...
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ژورنال
عنوان ژورنال: Current Opinion in Biotechnology
سال: 2016
ISSN: 0958-1669
DOI: 10.1016/j.copbio.2016.02.017