Tc1-mediated contact sensitivity reaction, its mechanism and regulation
نویسندگان
چکیده
منابع مشابه
[Tc1-mediated contact sensitivity reaction, its mechanism and regulation].
The contact hypersensitivity reaction (CHS) to haptens is a classic example of cell-mediated immune response. In the effector phase, two stages can be distinguished: an early component, that appears only 2 hours after subsequent contact with the hapten, and the late component that develops approximately 24 hours later which is mediated by TCRαβ+ cells. The effector lymphocytes may be CD4+ T hel...
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Cutaneous contact sensitivity (CS) is a subtype of delayed-type sensitivity and is mediated by either CD4(+) or CD8(+) CS-effector T cells. CS can be induced by skin painting with haptens like trinitrophenyl chloride (TNP-Cl).We have previously shown that CS is under the negative regulation of T regulatory cells (Treg) induced by the iv injection of a high dose of homologous antigen or via epic...
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ژورنال
عنوان ژورنال: Postępy Higieny i Medycyny Doświadczalnej
سال: 2014
ISSN: 1732-2693
DOI: 10.5604/17322693.1111925