TCT-829 Invasive Systemic Arterial Hemodynamics in Low Gradient Severe Aortic Stenosis with Preserved Ejection Fraction

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Invasive measures of afterload in low gradient severe aortic stenosis with preserved ejection fraction.

BACKGROUND The pathophysiology of low flow, low gradient severe aortic stenosis (LGSAS) with preserved ejection fraction is poorly understood. It has been proposed that abnormalities of arterial circulation are a major contributor to this syndrome. METHODS AND RESULTS We invasively examined systemic arterial afterload (effective arterial elastance, Ea; total arterial compliance, Ca; and syste...

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Systemic Hypertension in Low Gradient Severe Aortic Stenosis with Preserved Ejection Fraction

L ow-flow, low-gradient (LG) severe aortic stenosis (AS) with preserved ejection fraction (EF) is an increasingly recognized entity with discordant AS severity criteria that pose a clinical management dilemma. 1 Although treatment is controversial, it is generally recommended that such patients undergo aortic valve replacement when symptomatic and no other cause is found for symptoms. 2 However...

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Low gradient severe aortic stenosis with normal ejection fraction.

Sir, A 18 year old female patient was diagnosed to have tubercular cervical lymphadenopathy and started on antitubercular therapy (ATT). The lymphadenopathy regressed, however, after four months of ATT, patient developed jaundice, abdominal distension and swelling of bilateral lower limbs. She had no bleeding manifestation or altered behaviour. She had no history of jaundice in the past, histor...

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Low Gradient, Low Ejection Fraction Aortic Stenosis.

Low gradient aortic stenosis can be caused by critical aortic stenosis causing left ventricular impairment or by more moderate aortic stenosis coexisting with another cause of left ventricular impairment. The main challenges are to differentiate these two states and then to determine whether the left ventricle is likely to recover after aortic valve surgery. Exhaustive echocardiography is neces...

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Severe aortic valve stenosis with low-gradient and preserved ejection fraction: a misclassification issue?

INTRODUCTION AND OBJECTIVES Low-gradient severe aortic stenosis with preserved ejection fraction is a controversial entity. Misclassification of valvulopathy severity could explain the inconsistencies reported in the prognosis of these patients. Planimetry of the aortic area using three-dimensional transesophageal echocardiography could clear up these doubts. The objectives were to assess the a...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2012

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2012.08.875