Teaching NeuroImages: Distinct brain microhemorrhage pattern in critical illness associated with respiratory failure

Teaching NeuroImages: Distinct neuroimaging features of fucosidosis.

A 5-year-old girl, the product of nonconsanguineous marriage, presented with early-onset intellectual disability and autistic features. There was no regression, seizures, or vision or hearing impairment. She had normal head circumference, coarse facies, angiokeratomas, and lower limb rigidity. She had no cherryred spot or hepatosplenomegaly. Her 2-year-old brother had similar features with righ...

Teaching neuroimages: large vagal nerve schwannoma presenting with hemorrhage and respiratory failure.

A 30-year-old man was intubated after sudden severe headache, loss of consciousness, and apnea. CT showed acute hemorrhage in the posterior fossa, brainstem compression, and intraventricular extension with early obstructive hydrocephalus (figure 1A). MRI showed a large heterogeneously enhancing extra-axial tumor extending from the cerebellopontine angle to the foramen magnum (figure 1, B and C)...

Teaching NeuroImages: EEG pattern associated with a skull osteolytic lesion in breast cancer.

Teaching NeuroImages: neurodegeneration with brain iron accumulation in aceruloplasminemia.

A 55-year-old African Canadian man with insulin-dependent diabetes mellitus and alcohol abuse presented with diabetic ketoacidosis. Progressive cognitive decline over the previous 5 years resulted in long-term care placement. Aside from pigmentary retinopathy, general examination was unremarkable. MRI demonstrated iron accumulation in the brain (figure 1) and liver (figure 2A). Ceruloplasmin, a...

Teaching NeuroImages: Acute tetraparesis: Mind the brain.

A 65-year-old woman presented with acute tetraparesis. Neurologic examination showed severe leg paresis and mild proximal arm weakness, bilateral extensor plantar responses, hyperreflexia, and abulia. Brain MRI showed bilateral anterior cerebral artery (ACA) territory infarctions (figure). On evaluation, she had patent foramen ovale, deep venous thrombosis, and bilateral moderate carotid artery...