The Adequacy of Subendocardial Oxygen Delivery

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The adequacy of subendocardial oxygen delivery: the interaction of determinants of flow, arterial oxygen content and myocardial oxygen need.

oxygen delivery per unit of TTI was significantly lowered and Endo ECGs showed ischemia (ST elevation) when Endo/Epi flow ratios (microsphere method) fell below 1.0 (P < 0.001). Ischemia occurred without anemia (Hgb > 10 g %) in severe aortic stenosis; with mild anemia (Hgb 5-10 g %) and mild aortic stenosis; and with severe anemia (Hgb < 5 g %) without aortic stenosis. Ischemic Endo ECGs occur...

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Oxygen delivery to tissues.

For health, well perfused tissues, oxygen uptake is determined primarily by metabolic need rather than by oxygen supply. Tissue hypoxia supervenes when tissue oxygen tension (PO2) falls below a critical point, and the point where this occurs can be predicted from the systemic oxygen delivery or extraction ratio. A growing body of evidence suggest that tissue oxygen extraction may be impaired in...

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Oxygen delivery through capillaries.

During physical exertion the consumption rate increases and some cells suffer from the lack of oxygen. The time-wise evolution of hypoxia is analyzed mathematically under the condition the perfusion of each capillary is constant. The domain used contains multiple non-homogeneous capillaries of different solute out. Cells surrounding capillaries may consume or preserve more oxygen than are neces...

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Transtracheal oxygen delivery.

Conventional tracheostomies have been used for many years to deliver oxygen with the patient breathing spontaneously or in conjunction with positive pressure ventilators. The insertion of a transtracheal catheter specifically to deliver oxygen, however, dates only from Heimlich's studies published in 1982.' He showed that in dogs and man a normal oxygen saturation could be maintained by the del...

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Appropriateness of domiciliary oxygen delivery.

OBJECTIVE Almost every country in the developed world has a domiciliary oxygen program. Whether recipients meet program criteria has not been rigorously studied. DESIGN Cross-sectional survey. PARTICIPANTS Two hundred thirty-seven patients receiving domiciliary oxygen in the Ontario Ministry of Health Home Oxygen Program (HOP). METHODS A respiratory therapist visited the patients' homes a...

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ژورنال

عنوان ژورنال: Circulation

سال: 1974

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.49.5.968