The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC
نویسندگان
چکیده
منابع مشابه
Thrombin drives tumorigenesis in colitis-associated colon cancer.
The established association between inflammatory bowel disease and colorectal cancer underscores the importance of inflammation in colon cancer development. On the basis of evidence that hemostatic proteases are powerful modifiers of both inflammatory pathologies and tumor biology, gene-targeted mice carrying low levels of prothrombin were used to directly test the hypothesis that prothrombin c...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2015
ISSN: 0923-7534
DOI: 10.1093/annonc/mdv034