THE BIOMOLECULAR CHARACTERISTICS OF ANGIOTENSIN II TYPE 1 RECEPTORS AS PARAMETERS IN KIDNEY FIBROSIS: A BIOINFORMATICS ANALYSIS

AGTR1 is a modulator of angiotensin II-induced signal transduction. This article aims to examine the biomolecular characteristics and role in renal fibrosis pathway Rattus norvegicus rats. The gene ID NC 051352.1 protein NP 112271.2 for were retrieved from National Center Biotechnology Information's website. 'NCBI' website has details on AGTR1's structure, location, expression. Protease prediction using 'PEPTIDE CUTTER'; glycosylation index NETNGLYC; target location evaluated 'TARGETP' homepage. located chromosome 17p12, stability score 34.48. aliphatic was 114.62. found inside, outside, transmembrane, as determined by THMM. Only 21 enzymes predicted be capable cleaving protein, out total 37 protease. four glycosylated amino acid sequences. primarily at other 0.850, secretory (0.590), little amount mitochondria (0.018AGTR1/AT1R marker renin system, which can lead vasoconstriction, inflammation, fibrosis, sodium retention, water retention. protein's molecular feature determinant progression revealed bioinformatics study.