The central mechanism of hypothalamic-pituitary- adrenocortical system hyperfunction in depressed patients
نویسندگان
چکیده
منابع مشابه
Hypothalamic-pituitary-adrenocortical axis: neuropsychiatric aspects.
Evidence of aberrant hypothalamic-pituitary-adrenocortical (HPA) activity in many psychiatric disorders, although not universal, has sparked long-standing interest in HPA hormones as biomarkers of disease or treatment response. HPA activity may be chronically elevated in melancholic depression, panic disorder, obsessive-compulsive disorder, and schizophrenia. The HPA axis may be more reactive t...
متن کاملAlteration in the hypothalamic-pituitary-ovarian axis in depressed women.
BACKGROUND Stress and corticotropin-releasing hormone inhibit the reproductive axis. We hypothesized that reproductive axis hormone secretion, particularly luteinizing hormone secretion, is inhibited in women with depression, similar to what has been observed to be caused by stress in numerous species. METHODS Blood samples were collected every 10 minutes for 12 hours in 25 untreated premenop...
متن کاملThe hypothalamo-pituitary-adrenocortical system.
Control of the secretion of ACTH appears to involve several mechanisms. It is dependent upon the release, from neurones in the hypothalamus, of corticotrophin releasing factor, which is probably a complex including CRF-41 and vasopressin. The secretion of the complex is influenced by various central inhibitory and excitatory nervous pathways. The releasing factor is conveyed by the hypophyseal ...
متن کاملReliability of hormonal levels for assessing the hypothalamic-pituitary-adrenocortical system in clinical pharmacology.
Few data are available on the reliability of measurements of adrenocortical and corticotroph hormones for use in clinical pharmacology. Two placebo controlled cross-over trials in 20 normal healthy male subjects offered the opportunity to perform three repeat samplings of adrenocortical and corticotroph hormones at 1 to 5 week intervals during the placebo periods. Measurements of baseline level...
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چکیده: نسبت به کارکرد و ماهیت دیپلماسی عمومی در جهان امروز نظریه های متعددی بیان گردیده و جایگاه آن در کنار نظریه های دیگر در محافل آکادمیک و دانشگاهی بررسی و تحلیل گردیده است. نظر به اهمیت دیپلماسی عمومی و جایگاه آن در سیاست خارجی ایران این نوشتار با تمرکز بر دیپلماسی عمومی در منطقه آسیای مرکزی تهیه و تنظیم شده است. این ضرورت از آنجا ناشی می شود که اولاً مفهوم دیپلماسی عمومی در سیاست خارجی ای...
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ژورنال
عنوان ژورنال: Psychiatry and Clinical Neurosciences
سال: 2000
ISSN: 1323-1316,1440-1819
DOI: 10.1046/j.1440-1819.2000.00663.x